Preface-v
Acknowledgements-vii
How to Use This Book-ix
I: Basic Bacteriology-1
1. Bacteria Compared With Other Microorganisms-1
2. Structure of Bacterial Cells-4
3. Growth-15
4. Genetics-18
5. Classification of Medically Important Bacteria-24
6. Normal Flora-26
7. Pathogenesis-31
8. Host Defenses-52
9. Laboratory Diagnosis-61
10. Antimicrobial Drugs: Mechanism of Action-69
11. Antimicrobial Drugs: Resistance-87
12. Bacterial Vaccines-96
13. Sterilization & Disinfection-100
II: Clinical Bacteriology-105
14. Overview of the Major Pathogens & Introduction to Anaerobic Bacteria-105
15. Gram-Positive Cocci-109
16. Gram-Negative Cocci-128
17. Gram-Positive Rods-135
18. Gram-Negative Rods Related to the Enteric Tract-148
19. Gram-Negative Rods Related to the Respiratory Tract-171
20. Gram-Negative Rods Related to Animal Sources (Zoonotic Organisms)-177
21. Mycobacteria-183
22. Actinomycetes-194
23. Mycoplasmas-197
24. Spirochetes-199
25. Chlamydiae-208
26. Rickettsiae-212
27. Minor Bacterial Pathogens-217
III: Basic Virology-225
28. Structure-226
29. Replication-232
30. Genetics & Gene Therapy-244
31. Classification of Medically Important Viruses-248
32. Pathogenesis-253
33. Host Defenses-260
34. Laboratory Diagnosis-266
35. Antiviral Drugs-269
36. Viral Vaccines-280
PART IV: Clinical Virology-285
37. DNA Enveloped Viruses-288
38. DNA Nonenveloped Viruses-304
39. RNA Enveloped Viruses-311
40. RNA Nonenveloped Viruses-333
41. Hepatitis Viruses-342
42. Arboviruses-354
43. Tumor Viruses-361
44. Slow Virus & Prions-372
45. Human Immunodeficiency Virus-378
46. Minor Viral Pathogens-391
V: Mycology
47. Basic Mycology-397
48. Cutaneous & Subcutaneous Mycoses-403
49. Systemic Mycoses-407
50. Opportunistic Mycoses-414
VI: Parasitology
51. Intestinal & Urogenital Protozoa-424
52. Blood & Tissue Protozoa-433
53. Minor Protozoan Pathogens-450
54. Cestodes-453
55. Trematodes-462
56. Nematodes-469
VII: Immunology-489
57. Immunity-489
58. Cellular Basis of the Immune Response-500
59. Antibodies-522
60. Humoral Immunity-531
61. Cell-Mediated Immunity-534
62. Major Histocompatibility Complex & Transportation-536
63. Complement-542
64. Antigen-Antibody Reactions in the Laboratory-546
65. Hypersensitivity (Allergy)-557
66. Tolerance & Autoimmune Disease-567
67. Tumor Immunity-576
68. Immunodeficiency-578
VIII: Ectoparasites-585
69. Ectoparasites That Cause Human Disease-585
IX: Infectious diseases-593
70. Bone and joint infections-593
71. Caridac Infections-598
72. Central nervous system infections-605
73. Gastrointestinal tract infections-614
74. Pelvic infections-622
75. Upper respiratory tract infections-629
76. Lower respiratory tract infections-635
77. Skin and soft tissue infections-641
78. Urinary tract infections-649
X: Brief Summaries of Medically Important Organisms-653
XI: Clinical Cases-691
XII: Pearls for the USMLE-701
XIII: USMLE (National Board) Practice Questions-709
XIII: USMLE (National Board) Practice Examination-751
Index-761