Contributing Authors… v
Reviewer… vii
Illustration and Graphic Design…vii
UNIT I: Principles of Drug Therapy
Chapter 1: Pharmacokinetics…1
Chapter 2: Drug–Receptor Interactions and Pharmacodynamics…25
UNIT II: Drugs Affecting the Autonomic Nervous System
Chapter 3: The Autonomic Nervous System…39
Chapter 4: Cholinergic Agonists…51
Chapter 5: Cholinergic Antagonists…65
Chapter 6: Adrenergic Agonists…77
Chapter 7: Adrenergic Antagonists…95
Unit III: Drugs Affecting the Central Nervous System
Chapter 8: Drugs for Neurodegenerative Diseases…107
Chapter 9: Anxiolytic and Hypnotic Drugs…121
Chapter 10: Antidepressants…135
Chapter 11: Antipsychotic Drugs…147
Chapter 12: Drugs for Epilepsy…157
Chapter 13: Anesthetics…171
Chapter 14: Opioids…191
Chapter 15: Drugs of Abuse…205
Chapter 16: CNS Stimulants…215
Contents ix
x Contents x
UNIT IV: Drugs Affecting the Cardiovascular System
Chapter 17: Antihypertensives…225
Chapter 18: Diuretics…241
Chapter 19: Heart Failure…255
Chapter 20: Antiarrhythmics…269
Chapter 21: Antianginal Drugs…281
Chapter 22: Anticoagulants and Antiplatelet Agents…291
Chapter 23: Drugs for Hyperlipidemia…311
UNIT V: Drugs Affecting the Endocrine System
Chapter 24: Pituitary and Thyroid…325
Chapter 25: Drugs for Diabetes…335
Chapter 26: Estrogens and Androgens…351
Chapter 27: Adrenal Hormones…365
Chapter 28: Drugs for Obesity…375
UNIT VI: Drugs for Other Disorders
Chapter 29: Drugs for Disorders of the Respiratory System…381
Chapter 30: Antihistamines…393
Chapter 31: Gastrointestinal and Antiemetic Drugs…401
Chapter 32: Drugs for Urologic Disorders…415
Chapter 33: Drugs for Anemia…423
Chapter 34: Drugs for Dermatologic Disorders…431
Chapter 35: Drugs for Bone Disorders…441
Chapter 36: Anti-inflammatory, Antipyretic, and Analgesic Agents…447
Contents xi
UNIT VII: Chemotherapeutic Drugs
Chapter 37: Principles of Antimicrobial Therapy…471
Chapter 38: Cell Wall Inhibitors…483
Chapter 39: Protein Synthesis Inhibitors…499
Chapter 40: Quinolones, Folic Acid Antagonists, and Urinary Tract Antiseptics…513
Chapter 41: Antimycobacterial Drugs…525
Chapter 42: Antifungal Drugs…535
Chapter 43: Antiprotozoal Drugs…547
Chapter 44: Anthelmintic Drugs…561
Chapter 45: Antiviral Drugs…567
Chapter 46: Anticancer Drugs…587
Chapter 47: Immunosuppressants…619
UNIT VIII: Toxicology
Chapter 48: Clinical Toxicology…631
Index…641
Figure Sources…663