1. There are several updates and editions in the 14^th ed. Of Basic & clinical pharmacology by Bertram G. Katzung. The 14^thed. Of basic and clinical pharmacology continuous extensive use of full-color illustration and expanded coverage of transporters, pharmacology notices, and new drugs of all types emphasized in the prior edition. It is organized to reflect the syllabi in many pharmacology courses and in integrated curricula and covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. The selection of the subject matter and order of its presentation are based on the authors’ many years of experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.

1. "Basic & Clinical Pharmacology, 14th Edition" is a comprehensive textbook written by Bertram G. Katzung, Anthony J. Trevor, and Marieke Kruidering-Hall. It covers both the basic principles of pharmacology and the clinical applications of drugs, making it an essential resource for medical students, residents, and practitioners.

   The book is organized into 14 sections, starting with an introduction to pharmacology, drug receptors, and pharmacokinetics. It then delves into the pharmacology of various drug classes, including autonomic drugs, cardiovascular drugs, central nervous system drugs, and anti-inflammatory drugs. Each section covers the pharmacology of the drugs in that class, their mechanism of action, clinical uses, adverse effects, and drug interactions.

   The book also covers important topics such as pharmacogenetics, drug discovery and development, and drug regulation. It includes chapters on toxicology, herbal and dietary supplements, and drugs of abuse.

   The 14th edition features updated information on new drugs, new drug classes, and new treatments for various diseases. It also includes new chapters on drug-induced liver injury, pharmacogenomics, and the treatment of obesity.

   Overall, "Basic & Clinical Pharmacology, 14th Edition" is an authoritative and up-to-date resource that provides a comprehensive overview of the field of pharmacology, making it an essential reference for healthcare professionals at all levels.

1. The 14th edition of "Basic & Clinical Pharmacology" is a comprehensive textbook that covers the fundamental principles of pharmacology and their application to clinical practice. It is written by experts in the field and is designed to be used by medical students, residents, and practicing physicians.

   The book begins with an overview of pharmacology, including the history of drug development, pharmacokinetics, and pharmacodynamics. It then covers the major drug classes, including cardiovascular drugs, drugs that affect the central nervous system, antimicrobial agents, and anticancer drugs. Each drug class is discussed in detail, with information on their mechanisms of action, pharmacokinetics, clinical uses, and potential adverse effects.

   The 14th edition also includes new chapters on immunopharmacology, pharmacogenomics, and herbal and dietary supplements. It also features updated information on new drugs and advances in drug therapy, as well as clinical cases and multiple-choice questions to aid in self-assessment.

   Overall, "Basic & Clinical Pharmacology" is a valuable resource for anyone interested in understanding the principles of pharmacology and their application to patient care.

1. -Comprehensive coverage of pharmacology: Basic & clinical pharmacology provides an in-depth understanding of the pharmacological principles and their clinical applieatias.

   -Update content: The 14^th ed. Likely has updated content to reflect the latest developments in the field of pharmacology.

   -Clinical foeus: The book enqhasizer the clinical relevance of pharmacological concepts and their applications to patient case.

   -High quality illustrations tables: The book containg numous illustration and tables that help readers understand complex concept easily.

   -Case studies: Clinical case studies are integrated throughout the book to help studies understand how pharmacological concepts apply in real-life gituatious.

   -Drug summaries: The book provides detailed summaries of commenly used drugincluding this pharmacology clinical uses, adverse effects and drug interactions.

   -Online resources: The 14^th ed. Many include online resource such as a companion website that provides additional resources for  students and indruetaes Overall , basic & clinical pharmacology is a comprehensive and clinically focused pharmacology textbook that provides a thorough understanding of the principles and applieations of pharmacology.

"The fourteenth edition of Basic & Clinical Pharmacology continues the extensive use of full-color illustrations and expanded coverage of transporters, pharmacogenomics, and new drugs of all types emphasized in prior editions. In addition, it reflects the major expansion of large-molecule drugs in the pharmacopeia, with numerous new monoclonal antibodies and other biologic agents. Case studies accompany most chapters, and answers to questions posed in the case studies appear at the end of each chapter. The book is designed to provide a comprehensive, authoritative, and readable pharmacology textbook for students in the health sciences. Frequent revision is necessary to keep pace with the rapid changes in pharmacology and therapeutics; the 2-3 year revision cycle of this text is among the shortest in the field, and the availability of an online version provides even greater currency. The book also offers special features that make it a useful reference for house officers and practicing clinicians."

 The 14^th ed. Edition of basic & clinical pharmacology provides the latest information on drugs, drug therapies and advances in pharmacology. The book includes coverage of new and emerging drug and drugs classes, including immunotherapies and antiviral medieations. The impact of genetic variations on drug metaboliom and efficaey is also covered in the edition. More than B w full-color illustrations. are included to aid in understanding of drugs mecharism and pharmacology concepts. The book also contains updated information on drug interactions and this potertial  impact on treatment ahtemes. The 14^th ed. Of basic and clinical pharmacology by Katzung includes interactive features  such as quizzes, animation and flashcards to enhance learning . Overall this book alms to provide the most up-to-date and compre hensive information on pharmacology, including the latest drugs and drug therapies, as well as advances in pharmacogesnonies and peronalized medicine.

The fourteenth edition of Basic & Clinical Pharmacology continues the extensive use of full-color illustrations and expanded coverage of transporters, pharmacogenomics, and new drugs of all types emphasized in prior editions. In addition, it reflects the major expansion of large-molecule drugs in the pharmacopeia, with numerous new monoclonal antibodies and other biologic agents. Case studies accompany most chapters, and answers to questions posed in the case studies appear at the end of each chapter. The book is designed to provide a comprehensive, authoritative, and readable pharmacology textbook for students in the health sciences. Frequent revision is necessary to keep pace with the rapid changes in pharmacology and therapeutics; the 2–3 year revision cycle of this text is among the shortest in the field, and the availability of an online version provides even greater currency. The book also offers special features that make it a useful reference for house officers and practicing clinicians.
This edition continues the sequence used in many pharmacology courses and in integrated curricula: basic principles of drug discovery, pharmacodynamics, pharmacokinetics, and pharmacogenomics; autonomic drugs; cardiovascular-renal drugs; drugs with important actions on smooth muscle; the central nervous system drugs; drugs used to treat inflammation, gout, and diseases of the blood; endocrine drugs; chemotherapeutic drugs; toxicology; and special topics. This sequence builds new information on a foundation of information already assimilated. For example, early presentation of autonomic nervous system pharmacology allows students to integrate the physiology and neuroscience they have learned elsewhere with the pharmacology they are learning and prepares them to understand the autonomic effects of other drugs. This is especially important for the cardiovascular and central nervous system drug groups. However, chapters can be used equally well in courses and curricula that present these topics in a different sequence.
Within each chapter, emphasis is placed on the discussion of drug groups and prototypes rather than offering repetitive detail about individual drugs. The selection of the subject matter and the order of its presentation are based on the accumulated experience of teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.
Major features that make this book particularly useful in integrated curricula include sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects—in other words, clinical pharmacology is an integral part of this text. Lists of the trade and generic names of commercial preparations available are provided at the end of each chapter for easy reference by the house officer or practitioner evaluating a patient’s drug list or writing a prescription.

Significant revisions in this edition include:
• Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central
nervous system neurotransmitters.
• Continued expansion of the coverage of general concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters.
• Descriptions of important new drugs released through May 2017.
• Many revised illustrations in full color that provide significantly more information about drug mechanisms and effects and help to clarify important concepts.
An important related educational resource is Katzung & Trevor’s Pharmacology: Examination & Board Review, (Trevor AJ, Katzung BG, & Kruidering-Hall, M: McGraw-Hill). This book provides a succinct review of pharmacology with approximately one thousand sample examination questions and answers. It is especially helpful to students preparing for board-type examinations. A more highly condensed source of information suitable for review purposes is USMLE Road Map: Pharmacology, second edition (Katzung BG, Trevor AJ: McGraw-Hill, 2006). An extremely useful manual of toxicity due to drugs and other products is Poisoning & Drug Overdose, by Olson KR, ed; 7th edition, McGraw-Hill, 2017.
This edition marks the 35th year of the publication of Basic & Clinical Pharmacology. The widespread adoption of the first thirteen editions indicates that this book fills an important need. We believe that the fourteenth edition will satisfy this need even more successfully. Chinese, Croatian, Czech, French, Georgian, Indonesian, Italian, Japanese, Korean, Lithuanian, Portuguese, Spanish, Turkish, and Ukrainian translations of various editions are available. The publisher may be contacted for further information.
I wish to acknowledge the prior and continuing efforts of my contributing authors and the major contributions of the staff at Lange Medical Publications, Appleton & Lange, and  McGraw-Hill, and of our editors for this edition, Caroline Define and Greg Feldman. I also wish to thank Alice Camp and Katharine Katzung for their expert proofreading contributions.
Suggestions and comments about Basic & Clinical Pharmacology are always welcome. They may be sent to me in the care of the publisher.

Bertram G. Katzung, MD, PhD
San Francisco
June 2017