CHAPTER 1 Introduction and Organization of the Nervous System -1
Central and Peripheral Nervous Systems -1
Major Divisions of the Central Nervous System -2
Major Divisions of the Peripheral Nervous System-12
Early Development of the Nervous System-14
Clinical Notes-16
Clinical Problem Solving-27
Answers and Explanations to Clinical Problem Solving-28
Review Questions-29
Answers and Explanations to Review Questions-31
CHAPTER 2 Neurons and Neuroglia-33
Neurons-33
Neuroglia-54
Extracellular Space-60
Clinical Notes-62
Clinical Problem Solving-65
Answers and Explanations to Clinical Problem Solving-66
Review Questions-67
Answers and Explanations to Review Questions-69
CHAPTER 3_ Nerve Fibers and Peripheral Innervation-71
Nerve Fibers-71
Peripheral Nerves-80
Receptor Endings-84
Effector Endings-93
Segmental Innervation of Skin-98
Segmental Innervation of Muscles-100
Muscle Tone and Muscle Action-101
Motor Unit Summation-102
Muscle Fatigue-102
Posture-102
Clinical Notes-105
Clinical Problem Solving-119
Answers and Explanations to Clinical Problem Solving-122
Review Questions-125
Answers and Explanations to Review Questions-128
xi
xii Cord lntersegmental-131
Brief Review of the Vertebral Column-131
Ascending Tracts-142
Descending Tracts-152
intersegmental Tracts-160
Clinical Notes-163
Clinical Problem Solving-175
Answers and Explanations to Cllnlcal Problem Solving-177
Review Questions-180
Answers and Explanations to Review Questions-182
CHAPTER 5 Brainstem 1 as
Skull Anatomy-185
Introduction to the Brainstem-195
Medulla Oblongata-196
Midbrain-209
Clinical Notes-215
Clinical Problem Solving-219
Review Questions-222
CHAPTER 6 Cerebellum and Its Connections-229
Gross Appearance-229
Structures-231
Cerebellar Cortical Mechanisms-234
Cerebellar Afferent Fibers-236
Cerebellar Efferent Fibers-239
Functions of the Cerebellum-240
Clinical Notes-241
Clinical Problem Solving-244
Answers and Explanations to Clinical Problem Solving-244
Review Questions-245, 247, 249
Diencephalon-249
General Appearance of the Cerebral Hemispheres-255
Suki Cerebral Hemisphere Lobes-258
Internal Structure of the Cerebral Hemispheres (Atlas Plates 4 and 5)-260
Clinical Notes-267
Review Questions-275
xii Contents
CHAPTER 4 Spinal and Ascending, Descending, and
Intersegmental Tracts-131
Spinal Cord-136
Intersegmental Renshaw Cells and Lower Motor Neuron Inhibition -162
Clinical-185
Cranial Cavity-191
Pons-204
Answers and Explanations to Clinical Problem Solving-220
Answers and Explanations to Review Questions-226, 229
Answers and Explanations to Review Questions-247
CHAPTER 7 Cerebrum-249
Subdivisions-249
Main Sulci-256
Clinical Problem Solving-273
Answers and Explanations to Clinical Problem Solving-274
Answers and Explanations to Review Questions-277
Contents
xiii
The Structure and Functional Localization of the Cerebral Cortex-279
Structure-279
Cortical Areas-283
Cerebral Dominance-289
Answers and Explanations to Clinical Problem Solving-294
Review Questions-295
Answers and Explanations to Review Questions-297, 299
Reticular Formation-299
Limbic System-301
Clinical Clinical Problem Solving-307
Clinical Review Questions-307
Basal Nuclei (Basal Ganglia)-310
Terminology-310
Corpus Striatum-310
Amygdaloid Nucleus-311
Substantia Nigra and Subthalamic Nuclei-312
Connections of the Corpus Striatum and Globus Pallidus-312
Cllnical Answers and Explanations to Clinical Problem Solving-319
Review Questions-320, 323
Cranial Nerve Organization-323
Nerve I) 11) Trochlear Nerve (Cranial Nerve IV)-331
Facial Nerve (Cranial Nerve VII)-337
Vestibulocochlear Nerve (Cranial Nerve VIII)-339
Glossopharyngeal Nerve (Cranial Nerve IX)-341
Vagus Nerve (Cranial Nerve X)-343
Review Questions-358
Answers and Explanations to Review Questions-361
CHAPTER 8
CHAPTER 9
CHAPTER 10
CHAPTER 11
279
Cortical Mechanisms-283
Clinical Notes-290
Clinical Problem Solving-293
Reticular Formation and Limbic System-299
Clinical Notes-306
Answers and Explanations to Clinical Problem Solving-307
Answers and Explanations to Review Questions-308, 310
Striatum Claustrum-312
Basal Nuclei Functions-314
Clinical Notes-315
Clinical Problem Solving-319
Answers and Explanations to Review Questions-321
Cranial Nerve Nuclei-323
Cranial Nerves-323
Olfactory Nerves (Cranial Nerve!)-326
Optic Nerve (Cranial Nerve II)-327
Oculomotor Nerve (Cranial Nerve III)-331
Trigeminal Nerve (Cranial Nerve V)-332
Abducens Nerve (Cranial Nerve VI)-335
Vestibulocochlear Accessory Nerve (Cranial Nerve XI)-345
Hypoglossal Nerve (Cranial Nerve XII)-347
Clinical Notes-348
Clinical Problem Solving-356
Answers and Explanations to Clinical Problem Solving-357
xiv CHAPTER 12 Thalamus-363
General Appearance-363
Connections-366
Function-367
Answers and Explanations to Clinical Problem Solving-370
Review Questions-370
Answers and Explanations to Review Questions-372
CHAPTER 13-373
Hypothalamic Nuclei-375
Functions-380
Clinical Problem Solving-383
Answers and Explanations to Clinical Problem Solving-384
Review Questions-384
Answers and Explanations to Review Questions-385, 387
Organization-387
Autonomic Ganglia-390
Ganglion-Stimulating Agents-392
Blocking Other Postganglionic Transmitters-394
Higher Control-394
Enteric Nervous System-394
Differences Between Sympathetic and Parasympathetic Systems-395
Clinical Problem Solving-411
Review Questions-413
Answers and Explanations to Review Questions-416
CHAPTER 15-418
Brain Meninges-418
Clinical Problem Solving-432
Review Questions-434
Answers and Explanations to Review Questions-435
Contents
CHAPTER1 2-363
Subdivisions-363
Clinical Notes-369
Clinical Problem Solving-370
CHAPTER1 3 Hypothalamus-373
Hypothalamus-373
Hypothalamic Lines of Communication-376
Clinical Notes-382
CHAPTER 14 Autonomic Nervous System-387
Large Autonomic Plexuses-390
Preganglionic Transmitters-392
Fast, Slow, and Inhibitory Synaptic Potentials-392
Stimulating Ganglion-Blocking Agents-392
Postganglionic Nerve Endings-393
Postganglionic Transmitters-393
Cholinergic Receptor Blockade-394
Adrenergic Receptor Blockade-394
Enteric Functions-395
Autonomic Innervations-396
Ans Physiologic Reflexes-406
Clinical Notes-406
Answers and Explanations to Clinical Problem Solving-412
CHAPTER1 5 Meninges-418
Spinal Cord Meninges-425
Clinical Notes-428
Answers and Explanations to Clinical Problem Solving-433, 436
Ventricular System-436
Subarachnoid Space-447
Cerebrospinal Fluid-448
Blood-Brain and Blood-Cerebrospinal Fluid Barriers-452
Answers and Explanations to Clinical Problem Solving-459
Review Questions-460
Answers and Explanations to Review Questions-462, 464, 470
Cerebral Circulation-470
Spinal Cord Arteries-471
Spinal Cord Veins-472, 472
Clinical Problem Solving-480
Answers and Explanations to Clinical Problem Solving-482
Review Questions-484
Nervous System Development-488
Spinal Cord-488
Clinical Problem Solving-502
Review Questions-503, 507
Index 513
CCoonntetentnst s xv
CHAPTER 16 Ventricular System and Cerebrospinal Fluid-436
CHAPTER 17
CHAPTER 18
APPENDIX-447
Brain Blood—Cerebrospinal Clinical Notes-455
Clinical Problem Solving-458
Blood Supply of the Brain and Spinal Cord-464
Arteries of the Brain-464
Veins of the Brain-469
Brain Capillaries-470, 471, 472
Clinical Notes 472
Answers and Explanations to Review Questions 486, 488
Brain-490
Clinical Notes-498
Answers and Explanations to Clinical Problem Solving-503
Answers and Explanations to Review Questions-504
Neuroanatomical Data of Clinical Significance and Clinical
Neuroanatomy Techniques-507,
Index-513